Taosheng Chen, "A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery"
291 pages | CRC Press | 2009 | ISBN: 1420070509 | PDF | 5,4 Mb
Few scientists have access to the multidisciplinary experience needed for successful assay development and high-throughput screening (HTS) in drug discovery. Designed to give researchers a boost, this text integrates the experience of diverse experts who offer fundamental practical guidance across numerous situations. It introduces emerging technology that allows scientists to identify and capture relevant information. It instructs in how to initiate, validate, optimize, and manage a bioassay intended to screen large collections of compounds. It also identifies critical targets of relevance in drug discovery and treats each individually in terms of the parameters needed for successful assay development.